2025-2028：国家重点研发计划/合成生物学重点专项/项目

2025-2029：国家重点研发计划/合成生物学重点专项/任务

2025-2029：国家杰出青年科学基金

2023-2026：国家自然科学基金/面上项目

2022-2025：上海市优秀学术带头人

2020-2023：国家自然科学基金/面上项目

2019-2024：国家重点研发计划/高版本工业放线菌底盘/任务

2018-2021：国家重点研发计划/中药资源合成生物学研究/课题

2018-2021：国家自然科学基金/面上项目

2016-2019：国家自然科学基金/面上项目

2014-2016：国家优秀青年科学基金

2013-2016：国家自然科学基金/面上项目

2013-2015：教育部新世纪优秀人才支持计划

2010-2012：国家自然科学基金/青年项目

Wenya Tian, Guangzheng Wei, Borui Duan, Haidong Peng, Huanhuan Liu, Mengmeng Zheng, Zhi Lin, Zixin Deng, Zhengyu Zhang, Xudong Qu. Unveiling bacterial cytochrome P450 enzymes that catalyze steroid side-chain cleavage. Nat. Commun. 2026, 17, 581.

Kai Jiang, Yan Gao, Yuhan Dai, Xiaoli Yan, Lu Yang, Ming Jiang, Zhi Lin, Zixin Deng, Shukun Luo, Xudong Qu. Terminal carboxyl editing drives divergence in fasmacyin and anthrabenzoxocinone biosynthesis. J. Am. Chem. Soc. 2025, 147, 26468-26476.

Kai Jiang, Cheng Zhu, Xiaoli Yan, Guangjun Li, Zhi Lin, Ming Jiang, Zixin Deng, Shukun Luo, Xudong Qu. A stereoselective decarboxylative aromatase/cyclase directs the biosynthesis of an axially chiral biphenyl framework in fasamycin. J. Am. Chem. Soc. 2025, 147, 5596-5601.

Xiaoli Yan, Xinying Jia, Zhenyao Luo, Shunjia Ji, Meng-Jie Zhang, Hui Zhang, Mingjia Yu, Julie Orts, Kai Jiang, Zhi Lin, Zixin Deng, Xu-Dong Kong, Bostjan Kobe, Yi-Lei Zhao, Mehdi Mobli, Xudong Qu. An enzymatic dual-oxa Diels-Alder reaction constructs the oxygen-bridged tricyclic acetal unit of (-)-anthrabenzoxocinones. Nat. Chem. 2025, 17, 1058-1066.

Yeqing Du, Guangzheng Wei, Tai-Ping Zhou, Yuhan Dai, Wenya Tian, Mancheng Tang, Zixin Deng, Binju Wang, Xudong Qu. P450-mediated dual cyclization mechanisms for pyrroloindoline unit formation in bispyrrolidinoindoline diketopiperazine alkaloid biosynthesis. J. Am. Chem. Soc. 2025, 147, 45199-45209.

Guangzheng Wei, Borui Duan, Tai-Ping Zhou, Wenya Tian, Chenghai Sun, Zhi Lin, Zixin Deng, Binju Wang, Zhengyu Zhang, Xudong Qu. A Nucleobase-driven P450 peroxidase system enables regio- and stereo-specific formation of C‒C and C‒N bonds. Proc. Natl. Acad. Sci. USA 2024, 121, e2412890121.

Kai Jiang, Xu Chen, Xiaoli Yan, Zixin Deng, Shunkun Luo, Xudong Qu. An unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin. Proc. Natl. Acad. Sci. USA 2024, 121, e2321722121.

Chenghai Sun, Bao-Di Ma, Guangjun Li, Wenya Tian, Lu Yang, Haidong Peng, Zhi Lin, Zixin Deng, Xu-Dong Kong, Xudong Qu. Engineering the substrate specificity of a P450 dimerase enables the collective biosynthesis of heterodimeric tryptophan-containing diketopiperazines. Angew. Chem. Int. Ed. 2023, 62, e202304994.

Zhi Lin, Zhiwei Hu, Linjun Zhou, Benben Liu, Zixin Deng, Xudong Qu. A large conserved family of small molecule carboxyl methyltransferases identified from Microorganisms. Proc. Natl. Acad. Sci. USA 2023, 120, e2301389120.

Fuzhen Song, Mengmeng Zheng, Junlin Wang, Huanhuan Liu, Zhi Lin, Benben Liu, Zixin Deng, Hengjiang Cong, Qianghui Zhou, Xudong Qu. Chemoenzymatic synthesis of C14-functionalized steroids. Nat. Synth. 2023, 2, 729-739.