教育背景：

• 2011.09-2016.07    中科院上海有机所，有机化学，博士 （其中2015年在美国Scripps Research Institute学习）

• 2006.09-2010.07     复旦大学，药学，学士

工作经历：

• 2016年7月－2017年8月：博士后、Boston college (美国)

• 2017年8月－2020年8月：博士后、Scripps Research Institute (美国)

• 2021年2月-至今：长聘教轨副教授，博士生导师，上海交通大学变革性分子前沿科学中心

研究方向：

• 新型手性催化剂的设计，合成及不对称催化研究

• 核酸的高效合成方法开发，DNA编码化合物库（DEL）化学

科研项目：

1. 国家自然科学基金，22101171，2022-01至2024-12，在研，主持。

代表性论文：

1. Sun, S.-Z.; Cai, Y.-M.; Zhang, D.-L.; Wang, J.-B.; Yao, H.-Q.; Rui, X.-Y.; Martin, R.; Shang, M.* “Enantioselective Deaminative Alkylation of Amino Acid Derivatives with Unactivated Olefins” J. Am. Chem. Soc. 2022, 144, 1130.

2. Xiang, J.;§ Shang, M.; § Kawamata, Y.; Lundberg, H.; Reisberg, S.; Chen, M.; Mykhailiuk, P.; Beutner, G.; Gallego, G. M.; Starr, J.; Davies, A.; Paraselli, B.; Blackmond, D. G.; Baran, P. S. “Hindered Dialkyl Ether Synthesis via Electrogenerated Carboncations” Nature, 2019, 573, 398. (§contributed equally).

3. Shang, M.;§ Feu, K. S.,§ Vantourout, J. C.; Barton, L. M.; Osswald, H. L.; Kato, N.; Gagaring, K.; McNamara, C. W.; Chen, G.; Hu, L.; Ni, S.; Fernández-Canelas, P.; Chen, M.; Merchant, R. R.; Qin, T.; Schreiber, S. L.; Melillo, B.; Yu, J.-Q.; Baran, P. S. “Modular, Stereocontrolled Cβ-H/Cα-C Activation of Alkyl Carboxylic Acids” Proc. Natl. Acad. Sci.. U.S.A. 2019, 116, 8721.

4. Shang, M.; § Chan, J. Z.; § Cao, M.; Chang, Y.; Wang, Q.; Cook, B.; Torker, S.; Wasa, M. “C–H Functionalization of Amines via Alkene-Derived Nucleophiles through Cooperative Action of Chiral and Achiral Lewis Acid Catalysts: Applications in Enantioselective Synthesis” J. Am. Chem. Soc. 2018, 140, 10593.

5. Shang, M.; Wang, X.; Koo, S. M.; Youn, J.; Chan, J. Z.; Yao, W..; Hastings, B. T.; Wasa, M. “Frustrated Lewis Acid/Brønsted Base Catalyst for Direct Enantioselective α-Amination of Carbonyl Compounds” J. Am. Chem. Soc. 2017, 139, 95.

6. Shang, M.;§ Wang, M.-M.;§ Saint-Denis, T. G.; Li, M.-H.; Dai, H.-X.; Yu, J.-Q. “Cu-Mediated Late-Stage Functionalization of Heterocycle-Containing Molecules” Angew. Chem. Int. Ed. 2017,56, 5317.

7. Shang, M.; Cao, M.; Wang, Q.; Wasa, M. “Direct Enantioselective Mannich-Type Reaction of Ketones and Esters Using Frustrated Lewis Acid/Brønsted Base Catalyst” Angew. Chem. Int. Ed. 2017, 56, 13338.

8. Shang, M.; Shao, Q.; Sun, S.-Z.; Chen, Y.-Q.; Xu, H.; Dai, H.-X.; Yu, J.-Q. “Identification of Monodentate Oxazoline as a Ligand for Copper-Promoted ortho-C–H Hydroxylation and Amination” Chem. Sci. 2017, 8, 1469.

9. Shang, M.; Sun, S.-Z.; Dai, H.-X.; Yu, J.-Q. “Cu(II)-Mediated C–H Amidation and Amination of Arenes: Exceptional Compatibility with Heterocycles”, J. Am. Chem. Soc. 2014, 136, 3354.

10. Shang, M.; Sun, S.-Z.; Wang, H.-L.; Laforteza, B.N.; Dai, H.-X.; Yu, J.-Q. “Exceedingly Fast Cu(II)-Promoted ortho-C–H Trifluoromethylation of Arenes with TMSCF3” Angew. Chem. Int. Ed. 2014, 53, 10439.

11. Shang, M.; Wang, H.-L.; Sun, S.-Z.; Dai, H.-X.; Yu, J.-Q. “Cu(II)-Mediated ortho-C–H Alkynylation of (Hetero)Arenes with Terminal Alkynes” J. Am. Chem. Soc. 2014, 136, 11590.